The other day, my husband said to me, "So does this condition your sister has concern you at all about your own health?"   [smiley=yikes.gif]

I had not thought much about it.  Is there any kind of increased likelihood of me or my brothers having moyamoya because our sister does?  I saw some information about the genetic stuff, but frankly, I did not really understand it.

Anyone know?

Diane

Diane,
No one can say for sure about MM being genetic, however the cases I read about were from a parent with MM then their children having MM.
My son is the first on in the family to have a stroke, so I can't even say their is a history of strokes that might have been undiagnosed MM.
By my understanding then, my son has a higher chance of having children with MM, but my daughters chances are as low as the rest of the population.
Hope I didn't confuse you more.  :-/
Anyone have more info?  [smiley=huh.gif]
Rena

I have MM, and none of my 3 siblings have it. My daughter  is 5, and she is fine, also. I was always told that it wasn't genetic, but I have read about some cases where there are siblings with it. I think it's more from something environmental, than genetic. I will admit, I watch my daughter carefully, but so far, so good. I think cases where family members have it are interesting, but I still do not believe it is genetic. I hope I am right, I wouldn't want any of my siblings, or children to end up fighting it, too. If you have any doubts, see a neurologist, and run some tests, it may ease your mind.

Hope this helps??

Sara      :D  

hi my name is Sandy i have been told that i have the dominate gene for moyamoya there is a lot of test beimg done on my kids and i because all of my kids have mm i have 4 kids and 3 of them have mm the Dtr. said that they still have not pin pointed the gene

Noticed this recent change on the National Institute of Neurological Disorders and Stroke page (link is located on the links page) about moyamoya...

"Researchers suspect a genetic link because of the 9 percent incidence of the disease found in certain Japanese families. A gene for familial moyamoya disease has been located on chromosome 17q25 and further study of the gene may reveal the cause of the disorder."

Sounds promising!!

DJ, thanks for that info.It sure is interesting as well as promising.I hope this starts alittle more research in that direction.I have 3 children and watch my ohter 2 closely.It has always seemed so much more than just coincidence to see families with more than one child with such a rare disease.Also who knows what is in our backgrounds this has been miss diagnosed for so long.I have a huge history of strokes,"spells" as they were referred toback then, who knows what it was , Migraines, and Circle of Willis Aneurisms.It just seems tomuch of a coincidence.In fact my daughters first stroke was on the 20 yr anniversary of my fathers death from a cirlce of Willis aneurism,and the death of his father from a stroke.Sure was "creepy" .Thanks again for allthe info you supply here.
Mary Grace