Have any adult patients with MM had their children genetically tested? I have 7 and 4 year old boys, and wonder if they will develop the disease.

i dont have it but my daughter has it and i had my other daughter tested and they say she dont have it thank goodness

I am the only one in my Family that has MoyaMoya (MM). My genetic testing found minor MM like mutations on the MM genes, but my neurologist says I have MM. My brother was has migraines and was genetically and angiogram tested for MM but he does not have MM.

There are some on this site that are parent(s) with MM and they have a child with MM or there are two  siblings with MM and the parent(s) don't have it too.

MM is a strange disorder. My Husband and I are very concerned about passing it on when we have children, and it seems like from other discussions on this board that we should not worry about it. If the child presents symptoms then have it tested, if no symptoms then there is a high possibility that it will never develop MM.

I hope this helped.
Becky

TKMom,

I have asked the same questions. My children are in their early 20's. I have asked Mayfield Clinic in Cincinnati to include us in any genetic studies that they do. There was an article posted on this site from the Journal of Human Genetics. My Surgeon Dr. Zuccarello, MD from the University of Cincinnati and Mayfield Clinic says that now that we know about MoyaMoya Disease we should be aware of the symptoms and make sure we watch for those signs. My dad a retired Pharmacy Professor from the University of Cincinnati said that the research scientist only found 15% possibility in the cases studied. I am waiting to hear from my brother who is a research scientist with Amgen on what he thinks the article actually says. 

This has taken my family by surprise. I have been walking in Marathons for the past 10 years. I am hoping that this has helped some in my health and recovery. I am only one month post surgery. If you hear of any other studies please let me know. We are fortunate that the University of Cincinnati is very aggressive in doing research. 

I would like some more information about this genetic testing.  I wasn't aware that they had one.  I have four children . . . and one was diagnosed at the age of seven with moyamoya.  It has always been a concern (in the back of my mind) that another one of my children could be diagnosed. 

Kim -- mom to Matthew, 19, 3 strokes at 7 due to moyamoya