I apologize if this has been brought up before, but I was diagnosed with stage four Moya Moya in 1996, had surgeries, and came down with coronary artery disease a few years ago. Last week I had my fifth stent put in my heart. Has anyone heard of a correlation between Moya Moya and narrowing coronary arteries? My diet has already been heart-healthy, and I've lost 30 pounds and exercise daily for the last five months. My cardiologist says it's genetic, but I wonder if there is something else at play, i.e. Moya Moya. Any help is appreciated.

I was first diagnosed with coronary artery disease in 1998. I was told by my cardiologist that it is hereditary. I lost my brother and mother from this disease. In 2002 I had a stroke and fould I had moyamoya. My heart disease is not as severe as yours but I have to have an echocardiogram every six months. I had indirect bypass surgery for mm in 2003. I also feel the same as you. There is a connection.

Angiographical stages were classified by the criteria of Suzuki and Takaku.  I believe they are defined by the proliferation of the collateral vessels, and in the 4th stage the vessels start to disappear???  It's been along time since I read up on that topic.  Someone else could probably explain it much better, but I have definitely come across that in my review of the research.
Michele

I still have to send my stuff back to them. I can't seem to get us all together to get this done.  I was told I could call them and ask if they found the genetic markers for MM????  I'm still trying to get it all in to them.

I ended up calling the genetic counselor for the study and she said I was still part of it and haven't been contacted because I didn't have the genes they had found they thought had to do with MM.

My husband was diagnosed with MM aged 22 then went on to need heart by-pass on his 30 birthday. He died aged 42 my 2 sons aged 24 and 25 have both been diagnosed with MM and have had strokes so not so rare in this family.

Sorry for bringing this up yet again, but I'm hospital-bound for another angiogram and probably another stent or two the day after tomorrow. The blood flow on the left side of my heart is severely limited, according to a nuclear stress test I had a few days ago. I always thought Moya Moya would kill me eventually, as in massive stroke like my brother, but I have a suspicion that it's attacking my heart.

Just thought that I would mention that my husband has early onset of heart disease.  Two heart attacks by 45 years and 3 stints.  My daughter was diagnosed with moyamoya in March 2010 and they are doing genetic testing on both of them to see if there is a relationship with early onset of heart disease and moyamoya.  This is being done at Standford University Medical Center.

My daughter was nuclear stress tested in February to check coronary arteries and they were fine.

Corinne

Nuclear stress test measures blood flow through the coronary arteries, by injecting radioactive isotope and taking pictures with an imaging device, sorta like an xray. They found no blockahges this time and sent me home today.