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Does Moyamoya run in families? (Read 4401 times)
DianeMain
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My sister, PatM, has moyamoya.

Posts: 126
San Jose, USA, usa, 23, 160, CA, California
Gender: female
Does Moyamoya run in families?
Mar 17th, 2004 at 11:56pm
 
The other day, my husband said to me, "So does this condition your sister has concern you at all about your own health?"   Smiley

I had not thought much about it.  Is there any kind of increased likelihood of me or my brothers having moyamoya because our sister does?  I saw some information about the genetic stuff, but frankly, I did not really understand it.

Anyone know?

Diane
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Rena
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Hi, My son Tyler was diagnosed
with MM in 2003

Posts: 467
, Colorado, USA
Gender: female
Re: Does Moyamoya run in families?
Reply #1 - Mar 18th, 2004 at 8:08am
 
Diane,
No one can say for sure about MM being genetic, however the cases I read about were from a parent with MM then their children having MM.
My son is the first on in the family to have a stroke, so I can't even say their is a history of strokes that might have been undiagnosed MM.
By my understanding then, my son has a higher chance of having children with MM, but my daughters chances are as low as the rest of the population.
Hope I didn't confuse you more.  Undecided
Anyone have more info?  Smiley
Rena
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Sara
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I am 15 years post-op
and loving life!

Posts: 208
Houston, USA, usa, 291, 279, TX, Texas
Gender: female
Re: Does Moyamoya run in families?
Reply #2 - Mar 21st, 2004 at 12:00pm
 
I have MM, and none of my 3 siblings have it. My daughter  is 5, and she is fine, also. I was always told that it wasn't genetic, but I have read about some cases where there are siblings with it. I think it's more from something environmental, than genetic. I will admit, I watch my daughter carefully, but so far, so good. I think cases where family members have it are interesting, but I still do not believe it is genetic. I hope I am right, I wouldn't want any of my siblings, or children to end up fighting it, too. If you have any doubts, see a neurologist, and run some tests, it may ease your mind.

Hope this helps??

Sara      Cheesy
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sandy
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three of my children have
mm

Posts: 32
asheboro, USA, usa, 469, 186, NC, North_Carolina
Gender: female
Re: Does Moyamoya run in families?
Reply #3 - Apr 26th, 2004 at 2:45pm
 
hi my name is Sandy i have been told that i have the dominate gene for moyamoya there is a lot of test beimg done on my kids and i because all of my kids have mm i have 4 kids and 3 of them have mm the Dtr. said that they still have not pin pointed the gene
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DJ
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Been there, done that...

Posts: 721
Wichita, KS
Gender: male
Re: Does Moyamoya run in families?
Reply #4 - Apr 28th, 2004 at 2:05am
 
Noticed this recent change on the National Institute of Neurological Disorders and Stroke page (link is located on the links page) about moyamoya...

"Researchers suspect a genetic link because of the 9 percent incidence of the disease found in certain Japanese families. A gene for familial moyamoya disease has been located on chromosome 17q25 and further study of the gene may reveal the cause of the disorder."

Sounds promising!!
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mg12061
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Posts: 946
Albany, USA, usa, 492, 84, NY, New_York
Gender: female
Re: Does Moyamoya run in families?
Reply #5 - Apr 28th, 2004 at 11:27am
 
DJ, thanks for that info.It sure is interesting as well as promising.I hope this starts alittle more research in that direction.I have 3 children and watch my ohter 2 closely.It has always seemed so much more than just coincidence to see families with more than one child with such a rare disease.Also who knows what is in our backgrounds this has been miss diagnosed for so long.I have a huge history of strokes,"spells" as they were referred toback then, who knows what it was , Migraines, and Circle of Willis Aneurisms.It just seems tomuch of a coincidence.In fact my daughters first stroke was on the 20 yr anniversary of my fathers death from a cirlce of Willis aneurism,and the death of his father from a stroke.Sure was "creepy" .Thanks again for allthe info you supply here.
Mary Grace
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